A pioneering study by Chinese scientists researching autism spectrum disorder suggests that an unexpected ally – probiotics found in cheese – could offer a novel pathway for alleviating symptoms.
Autism spectrum disorder (ASD) is a lifelong neurological condition affecting social interaction, communication and behaviour that has an impact on more than 60 million people globally, with diagnoses rising annually.
Researchers from the Institute of Zoology at the Chinese Academy of Sciences explored the link between gut health and autism, building on growing evidence that gut microbiota may influence brain function, mood and cognition.
Their preliminary findings published in Cell Genomics on February 12 point to remarkable improvements in social behaviour in mice after they were treated with the probiotic Lactobacillus rhamnosus, which is commonly used in dairy fermentation.
ASD has long been associated with genetic and environmental factors, but recent studies highlight the gut-brain axis – a bidirectional communication system between the gastrointestinal tract and the central nervous system. Disruptions in gut bacteria have been linked to neurodevelopmental conditions, including anxiety and depression.
The research team, led by Institute of Zoology genomic scientist Zhao Fangqing, focused on the CHD8 gene, which is critical for brain and gut development. Mutations in CHD8 are among the most common genetic markers for autism.
